Description
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a well-known research compound originally developed for its role in cardiovascular and metabolic studies. It functions as an activator of AMP-activated protein kinase (AMPK), a key regulator of cellular energy balance. By mimicking the effects of exercise on a molecular level, AICAR has become a highly studied peptide in the fields of metabolism, endurance, and performance research.
Mechanism of Action:
AICAR works by activating AMPK, often referred to as the “metabolic master switch.” When AMPK is activated, it promotes glucose uptake and fatty acid oxidation, encouraging the body to utilize stored energy more efficiently. This mechanism has made AICAR a subject of research for conditions related to obesity, type 2 diabetes, cardiovascular function, and mitochondrial health.
Potential Research Benefits:
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Supports enhanced energy metabolism and endurance performance in models
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Promotes glucose regulation and insulin sensitivity
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Encourages fat oxidation and reduction of fat storage
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Investigated for cardioprotective properties
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Studied for potential in mitochondrial biogenesis and cellular energy support
Applications in Research:
Due to its unique ability to stimulate pathways similar to those activated by exercise, AICAR has been widely studied in metabolic research, obesity management models, and endurance-based applications. Its effects on energy regulation make it a valuable tool in exploring treatments for metabolic disorders and cardiovascular health.
Storage Guidelines:
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Store in a cool, dry place
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Protect from direct sunlight
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Reconstituted solutions should be stored under refrigeration (2–8°C)
