Description
Selank (Synthetic Peptide)
Selank is a synthetic peptide developed as a powerful anxiolytic and nootropic compound. Originally created by the Institute of Molecular Genetics of the Russian Academy of Sciences, Selank is derived from the naturally occurring tetrapeptide tuftsin, which plays a role in immune function. By modifying tuftsin and enhancing its stability, scientists created Selank to deliver sustained neurological and immunomodulatory benefits.
Key Benefits:
- Anxiolytic Effects: Selank is best known for its ability to reduce anxiety and stress without the sedative or addictive side effects of traditional medications like benzodiazepines.
- Cognitive Enhancement: It may support improved memory, focus, and learning capacity by modulating the balance of neurotransmitters such as serotonin and dopamine.
- Mood Stabilization: Selank helps promote emotional balance, making it useful for individuals dealing with chronic stress or mood disorders.
- Immunomodulatory Properties: Research suggests it can positively affect the immune system by influencing cytokine expression and promoting homeostasis.
- Neuroprotective Potential: Selank may also help protect brain cells from damage and support long-term cognitive health.
Mechanism of Action:
Selank influences several key systems in the brain, including the GABAergic, dopaminergic, and serotonergic pathways. It promotes the expression of brain-derived neurotrophic factor (BDNF), which is essential for neural plasticity and resilience. Additionally, Selank has been shown to inhibit the enzyme enkephalin-degrading enzymes, which may enhance mood and reduce pain perception.
Usage:
Selank is typically administered as a nasal spray or sublingual drop for optimal absorption and fast onset of action. It is used in both clinical and research settings to investigate its effectiveness in treating anxiety, depression, PTSD, and cognitive decline.
Important Notes:
- Not FDA-approved: Selank is currently not approved by the FDA and is intended for research purposes only in many countries.
- Well-tolerated: Clinical studies suggest it has a high safety profile with minimal to no reported side effects.
- Non-sedating: Unlike many anti-anxiety agents, Selank does not impair alertness or cause dependency.
Storage:
Store in a cool, dry place. If reconstituted, refrigerate and use within the recommended time frame.


